43 CrossRef citations to date 3 Altmetric Original Articles Synergistic Anti-Oxidative Effects of Lycopene with Other Bioactive Compounds

Lycopene belongs to the carotenoid family, which has more than 700 members. In human serum, only 14 caroteinoids have been identified, and, among these, lycopene was the most abundant. Lycopene is regarded as one of the most efficient singlet oxygen quencher and peroxyl radical scavenger of all the carotenoids and may represent an important defense … Continued

Lycopene inhibits disease progression in patients with benign prostate hyperplasia

Lycopene is a promising nutritional component for chemoprevention of prostate cancer (PCa). A possibly beneficial role of lycopene in patients diagnosed with benign prostate hyperplasia (BPH), who are at increased risk of developing PCa, has been suggested, although clinical data are lacking. Therefore, this pilot study aimed to investigate the effects of lycopene supplementation in … Continued

Supplementation with the antioxidant lycopene significantly decreases oxidative stress parameters and the bone resorption marker N-telopeptide of type I collagen in postmenopausal women

To date, no intervention studies have been published demonstrating the effect of the antioxidant lycopene on bone. Postmenopausal women supplemented with lycopene had significantly increased antioxidant capacity and decreased oxidative stress and the bone resorption marker N-telopeptide (NTx). Lycopene decreases bone resorption markers and may reduce the risk of osteoporosis.

Lycopene and other carotenoids inhibit estrogenic activity of 17 β-estradiol and genistein in cancer cells

Epidemiological evidence suggests that carotenoids prevent several types of cancer, including mammary and endometrial cancers. On the other hand, such studies have also shown that estrogens are the most important risk factors for these cancer types. Genistein, the phytoestrogen mainly found in soy, also shows significant estrogenic activity when tested at concentrations found in human … Continued